Peer-reviewed articles 17,970 +



Title: SURGICAL KERATECTOMY WITH KERATOPLASTY OF A MELANOMA IN A PERSIAN CAT USING VETRIX EYEQ GRAFT

SURGICAL KERATECTOMY WITH KERATOPLASTY OF A MELANOMA IN A PERSIAN CAT USING VETRIX EYEQ GRAFT
Elena BONEA; Ioan HUTU
10.5593/sgem2024v/4.2
1314-2704
English
24
4.2
•    Prof. DSc. Oleksandr Trofymchuk, UKRAINE 
•    Prof. Dr. hab. oec. Baiba Rivza, LATVIA
An ocular melanoma is a type of cancer that originates from the uncontrolled growth of melanocytes. In cats, melanomas are rare, with diffuse iris melanomas being the most common eye tumors. This case report describes an 8-year-old female Persian cat referred to our clinic for evaluation due to a dark spot extending to the cornea, obscuring vision, and unresponsive to prior drug treatments. Diagnosis was confirmed through histopathological examination of a tissue sample. The present case report details a complex keratectomy surgery performed to remove the melanoma, utilizing an amniotic graft to reconstruct the cornea. Initially, the procedure began as a straightforward keratectomy, but the melanoma's deep and superficial extension into the corneal tissue required filling the surgical gap with several layers of An-vision Vetrix® EyeQ amniotic graft for corneal reconstruction. The surgery was completed by applying a protective An-Bandage lens and suturing the external eye angle to reduce the palpebral fissure for added protection. Postoperatively, Vetrix EyeQ amniotic eye drops, An-HyPro eye gel, and antibiotic drops were administered for one month. The cat was reexamined at 1 week, and again at 1-, 6-, and 12-months post-surgery, with no signs of melanoma recurrence observed during follow-up. Our study demonstrates the feasibility of successfully removing the melanoma without enucleation, provided that proper surgical and postoperative management is applied, leading to favorable visual outcomes.
[1] Dubielzig RR, Ketring KL, McLellan GJ, et al. Veterinary Ocular Pathology: A Comparative Review. Edinburgh: Saunders Elsevier, 2010.
[2] Dubielzig RR. Tumors of the eye. In: Meuten DJ, ed. Tumors in Domestic Animals, 4th edition, Iowa State Press: Ames, 2002:739–54.
[3] Duncan D.E. & Peiffer R.L. 1991. Morphology and prognostic indicators of anterior uveal melanoma in cats. Progress in Veterinary and Comparative Ophthalmology. 1: 25-32.
[4] Grahn BH, Peiffer RL, Cullen CL, et al. Classification of feline intraocular neoplasms based on morphology, histochemical staining, and immunohistochemical labeling. Vet Ophthalmol 2006;9(6):395–403.
[5] Harris B, Dubielzig RR. Atypical primary ocular melanoma in cats. Vet Ophthalmol 1999;2:121–124.
[6] Kalishman JV, Chappell R, Flood LA, et al. A matched observational study of survival in cats with enucleation due to diffuse iris melanoma. Vet Ophthalmol 1998;1:25–29.
[7] Kayes D, Blacklock B. Feline Uveal Melanoma Review: Our Current Understanding and Recent Research Advances. Vet Sci. 2022 Jan 26;9(2):46. doi: 10.3390/vetsci9020046. PMID: 35202299; PMCID: PMC8877522.
[8] Krohne S.G. 1998. Ocular tumors of the dog and cat. In: Morrison W.B. (Ed). Cancer in Dogs and Cats Medical and Surgical Management. Baltimore: Williams & Wilkins, pp.731-758.
[9] Miller P.E. & Dubielzig R.R. 1996. Ocular tumors. In: MacEwen E.G. & Withrow S. (Eds). Journal of Small Animal Clinical Oncology. 2nd edn. Philadelphia: W.B. Saunders, pp.420-431.
[10] Patnaik AK, Mooney S. Feline melanoma: a comparative study of ocular, oral, and dermal neoplasms. Vet Pathol. 1988 Mar;25(2):105-12. doi: 10.1177/030098588802500201. PMID: 3363787.
[11] Pigatto, Joao Antonio Tadeu; Stieven Hunning, Paula; da Veiga Rodarte de Almeida, Ana Carolina; Quartiero Pereira, Fabianaaet al. Diffuse Iris Melanoma in a Cat. Acta Scientiae Veterinariae. 38(4): 429-432, 2010.
[12] Polton G, Borrego JF, Clemente-Vicario F, Clifford CA, Jagielski D, Kessler M, Kobayashi T, Lanore D, Queiroga FL, Rowe AT, Vajdovich P, Bergman PJ. Melanoma of the dog and cat: consensus and guidelines. Front Vet Sci. 2024 Apr 5;11:1359426. doi: 10.3389/fvets.2024.1359426. Erratum in: Front Vet Sci. 2024 Jul 02;11:1442751. doi: 10.3389/fvets.2024.1442751. PMID: 38645640; PMCID: PMC11026649.
[13] Stannard AA, Pulley LT: Tumors of the skin and soft tissues. In: Tumors in Domestic Animals, ed. Moulton JE, 2nd ed., pp. 16-74. University of California Press, Berkeley, 1978
[14] Wang AL, Kern T. Melanocytic Ophthalmic Neoplasms of the Domestic Veterinary Species: A Review. Top Companion Anim Med. 2015 Dec;30(4):148-57. doi: 10.1053/j.tcam.2015.06.001. Epub 2015 Jun 6. PMID: 27154598.
[15] Willis AM, Wilkie DA. Ocular oncology. Clin Tech Small Anim Pract 2001;16(1):77–85.
conference
Proceedings of 24th International Multidisciplinary Scientific GeoConference SGEM 2024
24th International Multidisciplinary Scientific GeoConference SGEM 2024, 27 - 30 November, 2024
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference Surveying Geology and Mining Ecology Management, SGEM
SWS Scholarly Society; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci and Arts; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; European Acad Sci, Arts and Letters; Acad Fine Arts Zagreb Croatia; Croatian Acad Sci and Arts; Acad Sci Moldova; Montenegrin Acad Sci and Arts; Georgian Acad Sci; Acad Fine Arts and Design Bratislava; Russian Acad Arts; Turkish Acad Sci.
325-332
27 - 30 November, 2024
website
10134
keratectomy, cat, melanoma, An-vision Vetrix eyeQ graft, an-Bandage lens

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