Peer-reviewed articles 17,970 +



Title: WATERBORNE SUCROSE IMPAIRS HEALTH STATUS OF FARMING FISH CARASSIUS AURATUS GIBELIO

WATERBORNE SUCROSE IMPAIRS HEALTH STATUS OF FARMING FISH CARASSIUS AURATUS GIBELIO
H. Falfushynska;O. Horyn;V. Khoma;G. Tereshchuk;L. Gnatyshyna
1314-2704
English
19
6.1
Glucose toxicity is a well-established being that has been proven in higher vertebrates. The goal of this the present study was to elucidate the response of farming fish gibel carp Carassius auratus gibelio to waterborne sucrose in low (5.55 mM, LS) and high (55.5 mM, HS) concentrations for 21 days mimicking carbohydrate-enrich diet. An increase in blood glucose levels, body mass and hepatosomatic indices were the common sign for both concentrations of sucrose. The treatment with low concentration of sucrose provoked prominent manifestations of oxidative stress traits, namely enhancement of reactive oxygen species (ROS), lipid peroxidation and lipofuscin in the liver. In contrast, exposure of fish to HS induced the oppression of stress response: the decreasing the levels of ROS and lipid peroxidation, accompanied by the elevation of DNA strand break, depletion of cholinesterase activity and enhancing of glycated hemoglobin. Treatment of carp with HS caused 50% mortality for 21 days. Substantially that hyperglycemia in LS and HS groups were accompanied by significant upregulation of stress-related proteins metallothioneins in the liver. Overall, gibel carp represents the prospective model for study hyperglycemia mechanisms and consequences in vertebrates. The appropriate level of carbohydrate in the diet of the farming fish is essential.
conference
19th International Multidisciplinary Scientific GeoConference SGEM 2019
19th International Multidisciplinary Scientific GeoConference SGEM 2019, 30 June - 6 July, 2019
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference-SGEM
Bulgarian Acad Sci; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci & Arts; Slovak Acad Sci; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; World Acad Sci; European Acad Sci, Arts & Letters; Ac
1045-1052
30 June - 6 July, 2019
website
cdrom
6485
gibel carp; hyperglycemia; metallothioneins; oxidative stress; cytotoxicity

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