Browse

Anthropogenic factors of the production environment of oil production are characterized by more intensive influence of these factors in contrast to the external environment, which can create the prerequisites for early development of adaptation disorders, functional changes in immune and humoral regulation, especially with their genetic determinism, and the formation of an increased risk of development and weighting of cardiovascular pathology in those engaged in oil production. The aim of the work was to study th...

Introduction. The Eastern region of the European part of Russia (Perms Krai) is characterized by the peculiarities of the wind regime, the presence of large highways and petrochemical enterprises. Aromatic hydrocarbons (AH) are highly prevalent in the environment and are found in emissions from vehicles and industrial plants. These substances belong to hormone-like xenobiotics, which are capable of making adjustments to the work of immune and hormonal regulation. Purpose of the work: analysis of the features and p...

Introduction. The extreme nature of environmental meteorological factors and the asynchronous change of day and night are considered to be one of the reasons leading to a decrease in the life quality in the Extreme North. These might lead to a violation of adaptive mechanisms under certain conditions. The combination of variants of polymorphic candidate genes causes functional disorders of the cardiovascular system. The research aims at studying the genetic polymorphism in children having pathologies of the cardio...

The peculiarities of ecological conditions determine different scenarios of adaptive changes in the immune and genetic status with the subsequent formation of eco-caused pathology. Purpose of the study: analysis of the peculiarities of the immunological and genetic status of the child population in the extreme conditions of the Arctic Circle of Russia under the combined impact of anthropogenic chemical and climatogeographic factors. Materials and methods . Immunological and genetic testing of 98 children (the terr...

The authors have conducted an experiment that involved modeling of interactions between immune regulation mechanisms applying a viral load simulator in vitro. The experiment was performed on a suspension that contained immune cells extracted from peripheral blood samples (68 samples overall). There were several influencing factors such as impacts exerted by managing elements including cytokines (IL-1), hydrocortisone, and exogenous environmental factors represented by aluminum compounds (aluminum oxide) as well as...