ANTICANCER AND ANTIBACTERIAL POTENTIAL OF METHOTREXATE LOADED IRON NANOPARTICLES PRODUCED BY GREEN SYNTHESIS METHOD
(STEF92 Technology, 2023-10-01, Tsvetelina Batsalova, Dzhemal Moten, Anastasiia Voronova, Balik Dzhambazov, A. Yu. Vasil’kov)
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An environmentally safe method - metal-vapor synthesis (MVS), was applied to produce iron nanoparticles (Fe NPs), which were conjugated with the drug methotrexate (MTX). The physicochemical properties and biological activity of the generated Fe NPs-MTX nanomaterials were analyzed. Transmission electron microscopy observations indicated that Fe NPs are stabilized in the form of aggregates with a size of 100 nm. The structure of these aggregates is similar to a -bunch of grapes-, which consists of metal particles ab...
