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Manure is characterized by a complex multicomponent composition and can be considered as a source of nutrients for microorganisms and plants. Moreover, manure has a high level of biogenicity. Therefore, this waste can be considered as the main resource for organic fertilizer production. Currently, there are many technological solutions for processing of renewable animal and poultry waste. Fast solid-phase fermentation of the organic feedstock is a most promising technology. Five technological solutions for the fer...

Currently, one of the priorities for sustainable development is human life getting better with functional foods. Non-dairy matrices are considered as promising alternative for production of foods and beverages with probiotic microbes. The development of these new products appears to be a hot area in which probiotic cereal beverages occupy a special place. The corn, buckwheat, oats, rye, wheat and barley flour was studied. Two-stage enzymatic hydrolysis of the water suspensions of the flour with amylases and protea...

The aim of the work was to optimize the process of obtaining multicomponent protein compositions with high biological value and higher functional properties than the original vegetable protein products. Was realized studies to obtain biocomposites on the base of pea protein-oat protein and pea protein-rice protein. Developed composites was enriched with all limited amino acids. For each of the essential amino acids, amino acid score was 100% and higher. Protein products used in this compositions are not in major a...

The results of extraction of pectin from beet pulp of sugar waste production have been presented. Production of pectin will allow you to avoid importing this product from abroad, as well as reduce the negative impact of sugar factories on the environment. The developed scheme is environmentally safe. For the production of jelly confectionery products of various assortment, pectin consumption ranges from 8 kg for citrus to 26 kg for beet pectin per 1 ton of finished products. In comparison with other gelling agents...

Symbiotic nitrogen fixation is the most environmentally friendly method for the accumulation of biologically bound nitrogen. Nitrogen fixation is carried out by bacteria, including from the class of ?-proteobacteria. Global climate changes lead to an increase of agricultural areas subjected to salinity. Current knowledge about the effect of high-salt stress on nitrogen-fixing symbiotic ?-proteobacteria has the appearance of a puzzle. The genetic mechanisms determining salt tolerance have been studied in the most d...

Modern industrial biotechnology considers extremophilic microorganisms and, in particular, extreme halophiles as promising producers for the bioeconomy of the future. Extremely halophilic bacteria and archaea can be used for the production of carotenoids, polyhydroxyalkanoates, polysaccharides, osmoprotectors, thermostable enzymes, photosystem proteins, and can also be sources of unique biologically active substances for medical purposes. The implementation of large-scale industrial processes with minimal requirem...

The main strategy of the world fishery complex is the development and implementation of technologies for deep processing of aquatic biological resources (WBR), including those that allow addressing the issue of filleting waste disposal. Using the existing technologies of processing, we get the amount of filleting waste of up to 80% or ~1.6 million tons of the average annual catch weight in the Russian Federation alone. However, it is known that fish skin and cartilage tissue are highly valuable technological raw m...

The antibiotic resistance is one of biosphere scale problem created by not only the medicine, but veterinary, food industry and animal husbandry. Bacteriocins are defined as ribosomally synthesized peptides with narrow or in some cases broad antimicrobial activity producing by various bacteria, especially against closely-related species. Among bacteriocin producers food-grade lactic acid bacteria (LAB) provide an increase interest due to their safety, preservative ability and potential probiotic properties. Unlike...

Currently, systems for encapsulating drugs are widely used to obtain drugs, since they provide both the preservation of the activity of the administered drug and the reduction of side effects from its administration on the gastrointestinal tract. Complexes of natural polysaccharides such as chitosan alginate and chitosan pectin are widely used as such carriers. These complexes have high biological resistance and biodegradability. In addition, they provide the release of the drug at neutral pH values, which corresp...

To date, there is an increase in the incidence of skin and subcutaneous tissue diseases, despite the variety of treatment methods. One of the promising class of biomaterials for the treatment of skin diseases can be coatings based on hydrogels. The purpose of this study was to obtain collagen-acrylic hydrogels with various technological parameters (varying the synthesis temperature and the degree of neutralization of acrylic acid) with the specified properties by radical polymerization. The chemical structure of t...

This study is devoted to studying the properties of a new polymer sorbent based on polyvinyl alcohol and carboxymethylcellulose using infrared spectroscopy and thermogravimetric analysis. The influence of calcium chloride on the performance characteristics of the sorbent, such as oil capacity, floatation, moisture content and polymer degradation, is studied. The cross-linked matrix has improved properties: increasing the oil capacity and flotation time, retention of the structure when the sorbent is on the water s...

The problem of obtaining compositions, that would act as biomaterials and fit all demands, is well-known. One the branch of application materials such is the hydrogels. High retention capacity of water and physiological fluids, sufficient physio-mechanical properties and safety of usage are ones of the most relevant specifications for medical hydrogels. It is quite hard to develop such formulations. Perspective initial substances for synthesis are gelatin (peptide native to human collagen) and tannin (natural comp...

Today, the analysis of the unique contribution to the formation of the ?genetic portrait? of regional features, including technogenic ones, which determines the occurrence of diseases and harm to health, is relevant. The use of modern critical genetic and cellular biotechnologies with the study of genetic polymorphism and thin cell subpopulations will allow us to catch the earliest violations of homeostatic indicators in geochemical technogenic provinces. The aim of the work is to assess the features of genetic in...

The study object is the research of the suitability of some maize hybrids (Zea mays L.) from Croatia. There were six cultivars of maize from Croatia: OSSK 403, OS 430, OSSK 515, OSSK 552, OSSK 617, OSSK 635 while as standard check was used hybrid NS 640 which is among the most used hybrids in Kosovo. Most of evaluated maize hybrids showed very high level of adaptability in agro-climatic condition of Kosovo. Six maize hybrids F1 generation from Croatia were tested, during the growing season, in agroclimatic conditi...

Fabrication of nanofibers is a field of research attracting a lot of interest from technologici scientists because of its great applications in many fields. In order to design the polymer drug delivery system, we had to select a polymer that is biocompatible, biodegradable, non-toxic and approved for medical use. One of the polymers that fulfill those requirements is poly (vinyl alcohol) (PVA). There have been various reports on the fabrication of PVA nanofibers with solvents as water, or water with different salt...

Within Europe 2020 Strategy the maxi Framework Programme Horizon 2020 cover a prominent role. SME Instrument is an implementation tool which had largely contributed to the development of innovative initiatives within the Small Medium Enterprises? system focusing on smart, sustainable and inclusive growth. SME instrument is staggered in three phases and the first two phases are the concrete vehicle to obtaining financing. This paper provides the concrete robustness of the accessions to 2019, i.e. the total number o...

The aim of the research is to develop multicomponent organic fertilizers based on nanostructured diatomite using organic waste and raw materials processing products, to study the indicators of agrophytocenoses and field crop yields. The paper uses the results of research on the development of multicomponent organic fertilizers, as well as their effectiveness in the experimental field of the Samara state agrarian UNIVERSITY in 2017-2019. (southern forest-steppe of the Volga region). One of the types of multicompone...

For increasing the volumes of the grain production and quality it is necessary to restore and extend sowing area, enlarge the yield growth at the expense of intensive technologies of cultivation, effective selection and decrease of losses while harvesting. One of the main reasons of yield shortage is lodging of sowings. This paper compares extent of grain crops lodging. The investigation was carried out using mathematic analysis of variety features of the stem resistance for winter and spring wheat, barley, rye, t...

Matrix metalloproteinases (MMP) belong to the family of zinc metalloprotenases, whose function is related to the metabolism of the extracellular matrix proteins. These enzymes play an important role in the development of physiological processes such as morphogenesis, resorption and tissue remodeling, migration, adhesion, cell differentiation and proliferation, as well as in pathological conditions (rheumatoid arthritis, glomerulonephritis, periodontitis, ulceration of the cornea, etc.). To the first, the most stud...

Alzheimer`s diseases (AD) is the most common age-related dementia, being characterized by accumulation of extracellular amyloid plaques in AD brains. The principal constituent of these plaques are fibrils which are primarily composed of amyloid-? peptides (A?), with 39-42 amino acid residues in length, which are the proteolysis products derived from the amyloid precursor peptide (APP). Several factors, such as oxidative stress, inflammation, metal ions or genetic factors are associated with AD. Even if metal ions ...

Natural dyes gained considerable attractiveness in textile manufacturing based on the negative impact of synthetic dyes on the environment and human health. The aim of the present study was to develop an efficient extractive technology of anthocyanins from Hibiscus sabdariffa, and to comparatively investigate the dyeing of cotton with the natural extract, in the presence and absence of (bio)mordants. The results of extraction processes using eco-friendly solvents and different solvent/solid ratio and extraction ti...

The paper suggests the use of diagnostic features in the form of decomposition coefficients of biosignals statistical estimates in the normal range and in different types of pathologies obtained on the basis of a mathematical model in the form of a cyclic random process. As a criterion for choosing the necessary spectral coefficients of the biosignal decompositions in the Fourier basis set, was chosen the energy criterion. As diagnostic features, was used a such spectral coefficients that according to the Bessel i...

This work is focused on antioxidant activity of various types of horticultural crops. Several types of vegetable and fruits were analyzed by free radicals scavenging method using 1,1-diphenyl-2-picrylhydrazyl (DPPH). In this work various methods of analysis results expressing were evaluated. The results were expressed, in terms of the widest applicability, while the simplicity of the serial analysis were maintained. Percentage of inhibition of free radicals was expressed per unit sample weight and standard pipetti...

The aim of this study was to evaluate the effects of plant biostimulants Agriful and Trichomil on selected quantitative and qualitative parameters of pepper fruits. To the small plot experiment were included 2 hybrid varieties: Kapirex F1 and Esperansa F1. The experiment was carried out in the unheated plastic tunnel in the Botanical Garden of the SUA in Nitra (Slovakia) in 2016 and 2017. We observed three variants: control (without application of biostimulants); Agriful variant (5 times application of Agriful at ...

Hazardous household waste (HHW) is a small but the most dangerous fraction of household waste. Different studies estimate their content in household waste from 0.1 to 1%. In Eastern Europe, due to the low efficiency of separate household waste collection, most of the hazardous household waste is mixed with other waste and are mainly disposed in landfills. A thorough analysis of the literature on HHW has been carried out. Statistical data on HHW generation in the Eastern Europe countries (Bulgaria, Czech Republic, ...

The solid waste generated in food industry was considered as a low cost raw material for the extraction of natural antioxidants. Unfortunately, some of these wastes are not dealt with properly and are causing considerable damage to the environment. Agricultural wastes in Romania amount range from 7600 thousand tons a year of which only 1400 thousand tons as animal feed and 1100 thousand tons as organic manure are being utilized. These crop waste results after harvesting in the farm of leaves stem which are charact...

Sinorhizobium meliloti species are saprophytic soil bacteria able to fix atmospheric nitrogen in symbiosis with host-plants from alfalfa cross inoculated group. These biotechnologically important species of rhizobia are commonly present in various soil environments, while little is known about their phages. The main objective of the research was to isolate and characterize phages (rhizobiophages) of S. meliloti from soil samples collected at the NE Caucasian origin of alfalfa diversity (NEC). Under our particular ...

Bacteriorhodopsin (bR) is a red-colored protein found in cell membranes of the organism Halobacterium salinarum, being considered as a light activated proton pump that transports protons across the plasma membrane. Because bacteriorhodopsin is one of the simplest ATP-producing systems known in biology, it has been the subject of intensive investigations. The bR photo-intermediates were seen in the mechanistic model considering that this protein links light energy to the translocation of protons across the bacteria...

Baltic sprats, being one of the primary fishing objects of the Baltic Sea, are primarily used for canned and spiced fish production. Given the ability of sprats to ripen in salt, the current study looks to obtain sprat-based products implementing the technological scheme similar to the production scheme of anchovies in oil and anchovy pastes popular on the European market. As part of the preliminary work, the technochemical composition of the Baltic sprat and that of the European anchovy (Engraulis engasicholus) w...

Neurodegenerative diseases are a group of pathologies that mainly affect neurons of the human brain. Particularly, Alzheimer disease (AD) is a neurodegenerative disorder, being manifested by neuronal and synaptic loss. One of the main pathological aspects of AD is aggregation of amyloid-? (A?) peptide. However, there are some neuropeptides that play an important role in immunity and neuroprotection. In addition, the presence of metal ions and their abnormal accumulation play a key role in this pathology. The inter...

Chicken manure is one of the massively produced wastes in the agriculture, and pyrolysis may be a good way of its treatment. Biochar obtained in the process of pyrolysis may be used as soil fertilizer since it improves soil water and air balance, stabilizes pH, provides plants and soil microbiota with nutrients. In the present study, chicken manure with sawdust was pyrolyzed at 400 ?C (residence time 2 h), and biochar obtained was added to soil in a dose of 30 t ha-1 in a field experiment. Wheat was planted in the...

In view of increasing demand for more efficient use of water resources, technological processes are innovated in textile industry and result in lower environmental impact. One possible option is to clean textile waste water containing industrial dye residues by microbial consortia and biodegradation process. This method of removing potentially toxic substances by microbial biomass is appropriate because other chemicals are not brought into the environment and residual biomass can be easily removed when the biodegr...

One of the directions of the rational use of the secondary raw materials of meat industry, including collagen-containing, is its modification in order to obtain protein products enriched with micronutrients for the further use in food production. The presence of active carboxyl end groups in the collagen molecule and complex spatial structure cause the complexation of this protein with various minor nutrients, thereby promoting the creation of a biologically active composite for the enrichment of meat products. To...

Despite biohydrometallurgy is widely used worldwide, new approaches are developed to increase its efficiency, for example, two-stage biohydrometallurgical processing of sulfide concentrates. In the first stage, raw material is leached with ferric sulfate solution at high temperature. In the second stage, Fe3+ ions in the pregnant solution should be regenerated using microorganisms. Screening of the microorganisms, which are capable of active ferrous iron concentration, is important for the development of novel bio...

Biohydrometallurgical technologies are widely used for the extraction of non-ferrous and precious metals from sulfide ores and concentrates including gold-bearing refractory concentrates. Biohydrometallurgical treatment of gold-bearing sulfide concentrates is based on the oxidation of sulfide minerals by acidophilic microorganisms oxidizing ferrous iron and sulfur. This makes it possible to increase gold extraction by subsequent cyanidation as biooxidation results in disruption of crystal lattice of sulfide minera...

Many works are devoted to the problem of obtaining healthy drinks. The paper discusses various aspects of obtaining the probiotic drink from grain raw materials and concentrate for its preparation. Wheat malt was used as the raw material. The following strains of the lactic acid bacteria were used to manufacture a probiotic beverage: Lactobacillus plantarum, Lactobacillus fermenti, Lactobacillus brevis and acid-resistant yeast Saccharomyces cerevisiae TUM 175. The most good organoleptic and physico-chemical indica...

The research regarding some technological links took place in the Oravita Depression, located in south-western Romania, between 2016 and 2018. The records from the Oravita Meteorological Station show that the average annual rainfall in the area is 736 mm, and the average annual temperature is 10°C. The climate of this area falls within the climatic formula c.f.b.x. according to Koppen, namely in the moderate continental temperate climate. The soil type on which the experiments were performed was stagno-gleyic prel...

The compositions of polymer biodegradable films based on polyhydroxybutyrate and chitosan, cross-linked with calcium chloride, have been developed. New materials, which are promising for use in the field of medicine as wound coverings, suture materials and tissue engineering, have been obtained by casting method. The effect of prescription parameters such as the content of plasticizer and calcium chloride on the physic-chemical properties of polymer compositions has been studied. It is shown that by varying the co...

One of the risk factors in skin cancer is unprotected exposure to UV radiation. Melanoma is the deadliest form of skin cancer but also curable if it is diagnosed in the early stages. This study uses a histogram analysis technique to investigate and classify two common skin lesions, nevi and melanoma. The colour feature investigated is the optimal threshold values in RGB space. Also, a boundary limit of the skin lesions is performed using a colour histogram analysis and the optimal threshold determination. A statis...

At present, the issue of rational use of meat, taking into account the peculiarities of autolysis, is of particular importance, since the production of animals for meat processing increased, after slaughter of which significant deviations in the development of autolytic processes are found in muscle tissue. Therefore, a comparative assessment of changes in the indices of beef DFD and NOR, taking into account the influence of various freezing parameters, is highly relevant and is of scientific and practical interes...

To purify wastewaters, milk processing plants use different methods, but the sorption method is the most affordable and effective. Among the various types of adsorbents, natural zeolites that have adsorptive and ion-exchange properties deserve special attention, which makes them attractive for use in agriculture as a soil amendment. The objective of the work is to develop and implement the algorithm of comprehensive evaluation and simulation of the effectiveness of the combined application of spent zeolite and pre...

Enzymatic conversion of lignocellulosic substrates into sugars is an upcoming sphere of biotechnology. Most of the ways, aimed on hydrolysis process improvement are focused at maximizing of raw materials conversion into monosaccharides. Thus, process improvement usually focuses on substrates pretreatment, choosing of the most effective enzyme complexes and control of the hydrolysis process parameters such as increasing the process duration and enzyme dosage, substrate concentration reduction. Kraft woody pulp enzy...

Metallurgy is currently faced with difficulties due to the depletion of easily processed mineral raw materials. Thus, the development of new technologies for processing of low-grade sulfide ores and substandard concentrates is an urgent task. Biohydrometallurgical methods based on the activity of acidophilic microorganisms can be used to extract metals from different sulfide concentrates including arsenic-containing. The treatment of these products using pyrometallurgical technologies poses a problem due to the lo...

The growth in the value of functional nutrition for person?s life is due to a number of factors leading to poor health, such as unfavorable environmental conditions, urbanization of society, increased infectious load (bio-burden of pathogens) as a result contact with many people. Prebiotics are the most common food ingredients, along with probiotics used in functional foods. Since the second half of 1990, a huge amount of research has been carried out to prove the prebiotic properties of certain substances or comp...

The blood-brain barrier (BBB) is a functional structure of the brain that regulates the penetration into the Central nervous system of many foreign, toxic substances and compounds that penetrate into the blood or formed in the body itself, including drugs that can harm the nerve cells of the brain and spinal cord. BBB is not an insurmountable barrier separating the Central nervous system from the General internal environment. Its impermeability depends on the concentration and amount of substances in the blood, as...

The main factor destroying the biosphere of the Planet is the increasing amount of industrial waste. Herewith, production bio-waste from health care and animal husbandry categorical objects plays a special role in generating infectious agents with unpredictable pathogenic potential. The most reliable way to disinfect them is the technology of elementary heat recovery. At the same time, in the 21st century this approach to clean up the territories from biocontaminants seems unacceptable for biosphere. Taking into a...

This study was conducted to determine the effects of various levels of dietary protein and short-term starvation periods on compensatory growth, body compositions and organ indices of rainbow trout (Oncorhynchus mykiss) during 46 days. Fish were fed ad libitum twice a day or starved as follows: two control groups, one group was feed daily with extruded pellets containing 41% crude protein (D41) and the other control group was feed daily with commercial pellets containing 50% crude protein (D50); two groups fasted ...

A research of edible gelatin rainbow holograms is presented. Gelatin is an edible material with optical properties: it is transparent in the visible region of the spectrum and has refractive index close to refractive index of optical polymers. Gelatin is capable to transfer diffraction relief and save it for a long time. Gelatin holograms were prepared by nanoimprinting method from gelatin aqua solutions with different concentrations (1 part of gelatin per 5, 10, 15, 20, 25 parts of water). The samples were made o...

Vegetables are considered a rich source of antioxidants (flavonoids, carotenoids, vitamins), which are frequently added to stop the process of oxidation in processed food systems. The solid waste generated in food industry was considered as a low cost raw material for the extraction of natural antioxidants. The effect of drying techniques (ambient-drying and oven-drying) on the total phenolic contents and antioxidant activity of selected vegetables byproducts (garlic (Allium sativum L.), tomato (Lycopersicon escul...

Acidophilic microorganisms oxidizing ferrous iron and sulfur are widely used in hydrometallurgy to extract different metals including copper, zinc, nickel, cobalt, and uranium from sulfide ores. The activity of microorganisms and screening of microbial strains capable of biooxidation of ferrous iron and sulfur compounds under different conditions, i.e. in the present of different toxicants, which may be present in treated ores, are crucial for the development of biohydrometallurgical technologies. Different factor...